Cart
sales@molnova.com
SJF 1521
CAS No. 2230821-40-4
SJF 1521( —— )
Catalog No. M34826 CAS No. 2230821-40-4
SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 935 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSJF 1521
-
NoteResearch use only, not for human use.
-
Brief DescriptionSJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.
-
DescriptionSJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 contains the EGFR inhibitor lapatinib (HY-50898). SJF-1521 can induce EGFR degradation in OVCAR8 cells.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorPROTACs | EGFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2230821-40-4
-
Formula Weight1074.65
-
Molecular FormulaC57H61ClFN7O9S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C=1C2=C(C=CC(=C2)C3=CC=C(OCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)[C@](C)(C)C)=O)C=C3)N=CN1)C7=CC(Cl)=C(OCC8=CC(F)=CC=C8)C=C7
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Burslem GM,et al. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell Chem Biol. 2018 Jan 18;25(1):67-77.e3.?
molnova catalog
related products
-
Cbz-NH-PEG1-CH2CH2CO...
Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Aptal
Chlorocresol is an activator of ryanodine receptor.
-
STK16-IN-1
STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).
